ABSTRACT
This study was conducted to compare the vein graft with the nerve graft, and evaluated the availability of the vein graft on the reconstruction of the inferior alveolar nerve defect. The experimental animals were 12 rabbits weighing 1.5~2.0kg, divided into 3 groups : sham operation group, vein conduit group and nerve graft group. All nerves were excised and histomorphometric analysis was performed at 2, 4, 6, 12, 16 weeks after operation. The obtained results were as follows. 1. Histologic examination revealed the regenerated nerve fibers within the lumen of the vein graft and nerve graft at 6 weeks after repair. 2. Axon diameter was significantly larger in nerve graft group(p<0.05) than in vein graft group at 6weeks, and larger in nerve graft group than in vein graft group at 16weeks. 3. Axon density was higher in the vein graft group at 16 weeks. 4. The myelin of the regenerated nerve fibers in distal segment of the vein graft group was thick, approaching the proximal segment at 16weeks. This means remyelination in distal segment in the vein graft group. These results suggested that autogenous vein graft may be used as an alternative to autogenous nerve graft.
Subject(s)
Animals , Rabbits , Axons , Mandibular Nerve , Myelin Sheath , Nerve Fibers , Regeneration , Transplants , VeinsABSTRACT
The changes of the microorganism composition after therapeutic radiation for oral cancer patients are not well known and the long-term follow-up data are not reported. To obtain basic data for understanding of pathogenesis and prevention and treatment of dental caries and mucositis occuring after radiation therapy, 7 of the oral cancer patients presented at the Seoul National University Oral & Maxillofacial Department between 1997 and 1998 whose treatment plan included radiation therapy were recruited to investigate the changes in bacterial composition(total aerobic count, candida, Staphylococci, lactobacilli, S. mutans, and S. salivarius (mitis, sanguis)) of the saliva before, during, and after radiation therapy. The basic data obtained from this study on identification and composition change of the bacteria in saliva of patients treated with radiation therapy can be used (1) as a reference for deciding on the ideal anti-microbial spectrum of the oral rinsing agent to be used in patients treated with radiation therapy for malignant tumor of the head and neck region. (2) to enhance the understanding of increase of opportunistic infection after immunochemical changes of the saliva and its relation to specific bacterial infection. (3) as a reference in prescribing prophylactic antibiotics in immunodepressed patients after radiation therapy.
Subject(s)
Humans , Anti-Bacterial Agents , Bacteria , Bacterial Infections , Candida , Dental Caries , Follow-Up Studies , Head , Mouth Neoplasms , Mucositis , Neck , Opportunistic Infections , Saliva , SeoulABSTRACT
Subject(s)
Humans , Male , Coloring Agents , Cytomegalovirus , Endothelial Cells , Intranuclear Inclusion Bodies , Methenamine , Mouth , Oral Manifestations , Stomatitis , Tongue , UlcerABSTRACT
Many authors reported the etiology of hypoplasia of the nasomaxillary complex as trauma, infection, underdevelopment. To correct these deformities, Le Fort II Osteotomy and its modification has been popularly applied. This method enabled total advancement of nasomaxillary complexes and acquirememt of midfacial esthetics. But it has some limitations such as various occlusal deviation or lateral shifting of nasomaxillary complex in case of nasomaxillary retrusion. We grouped these patients as follows : 1. Nasomaxillary retrusion without shifting of nasomaxillary complex (1) Anteroposterior deviation of occlusal plane (2) Lateral deviation of occlusal plane(including canting) (3) Supero-inferior deviation of occlusal plane (4) Combined disturbance of occlusal plane without shifting of nasamaxillary complex 2. Lateral shifting of nasomaxillary complex with or without deviation of occlusal plane We performed Le Fort II and I combined osteotomy on eleven cases of midfacial deformity from June 1994 to July 1997 and in most of the cases, followed up maximum 36 months and could acquire positional stability and improvement of facial eathetics.
Subject(s)
Humans , Congenital Abnormalities , Dental Occlusion , Esthetics , OsteotomyABSTRACT
No abstract available.
ABSTRACT
In all patients with oral and maxillofacial surgery under the general anesthesia from January 1986 to December 1988, a clinical analysis had been made on preperative physical status, preoperative complicating medical disease ar abnormal laboratory finding, intubation and anesthetic agent used including the age and sex distribation of patients and the surgical lesion. The following results were obtained: 1) The male patients were 1.3 times more than the female in sex distribution 2) The patients between 20 and 29 years old were the most in age distribution 3) The benign tumors were the most common surgieal lesion(20.2%) 4) Of the 1393 patients with oral and maxillofacial surgery, the l34 patients were observed to have the underlying medical diseases or abnormal laboratory findings preoperatively(9.6%). In these patients the abnormal findings on E. K. G were most common. 5) Of the l393 patients, the 1170 patients were classified physical status l. and there were 206 patients of physical status 2 and 17 patients of physical status 3. 6) Of 1393 patients, the intubation were performed through tracheostomy in 6 patients and the fiberoptic endoscope were used to secure the endotracheal intubation in 20 patients. In 3 patients the blind nasotracheal intubation were made to secure the endotracheal intubation. 7) The conventional laryngoscopic instrumentations for the oral or nasotracheal intubation were performed in 1355 patients(97.3%). 8) The use of O2, N2O and halothane for the general anesthesia was the most common method for the general anesthesia.